I am considering an Alaskan Cruise this fall with my wife. Any recommendations as to which cruise line and/or itinerary you would recommend?

I have been hunting up there once and would like to see the sites along the coast as well. Other recommendations as to enjoying Alaska would be appreciated - I do not plan on hunting this time around.

Not sure Alaskan residents would really like the cruise folks showing up in their beautiful state so please be patient with my question -- I am also interested in cruise lines that respect the locals as best they can