I loaded some 375s for a friend. I believe the bullets were 225 grains and I used 60 to 61 grains of IMR 3031. They were accurate and were stepping out @ 2400 ft/sec. Recoil was acceptable to this 140 pound man. I thought it was similar to a 30-06 220 grainer.

"Keep thy heart with all diligence; for out of it are the issues of life." (Prov 4:23)

Brother Keith