One of the interesting aspects for me is teams who start out with issues are able to correct them at some point in the season. Aggy for instance has a green backup QB and same for some of their OL. OU's defense has talent and plays well for portions of the game but are inconsistent. Same can be said for their QB. They typically will iron out those kinds of wrinkles when they have them by the time the RRS game arrives. Do or die kind of deal, hahaha. But it's not a given.
Just some random pickings, but the notion that teams can get better or worse (injuries?) as the season progresses is an aspect I pay attention to. Sometimes it's better for a team to catch an opponent earlier in the season than later.
