This is apples to oranges, but I shared camp with two guys in Newfoundland that were using 178grn ELDX's out of a .308 and a .30-06.
The guy with the .308 shot a woodland caribou at about 40 yards, quartering away. The bullet barely made it through one lung.
The guy with the 06 shot a decent bull moose perfect broadside, at about 60 yards. Hit it 4 times and had time to get in his backpack and reload before it dropped and then had to finish it with another round.
Very poor penetration in all cases.