For single shots I prefer the rimmed 45-70 all day long. For modern rifle design like the BLR or bolt action the 450marlin is the winner. Ballistic twins pretty much.

If they were equally available and popular I'd prefer the 45-70 for my single shots and the 450marlin for more modern designs like my Browning BLR. I feel that the 450marlin actually addresses a few safety issues quite well and intelligently but it never took off. I wanted a takedown 45-70 but never wanted to pay the Wild West Guns tariff so my BLR takedown filled that niche.