Unless you're using a maximum load, the same charge will be fine as far as safety. However, I'd go a step further and vary the charge a little up and down and shoot some groups from a 25 yard benchrest. It may make no difference at all, but I got slightly tighter groups with a magnum primer as opposed to a standard primer in a 6" Python using #2400 and a 160 grain cast bullet, the H&G #51. Been a long time ago and don't remember the primer brands, but it's worth trying.

Last edited by lotech; 06/02/22.