I've shot about 6# of True Blue in a 40 S&W with 180 gr bullets and 4# in a 45 ACP using 230 gr bullets. I've been very happy with it and would buy more if I needed more pistol powder.
I had similar concerns regarding the density but my concerns have been unfounded. I wish I would have thought to try it in the 25 and 32 ACP.
