I've run everything from 3/4" K-Mart Tasco scopes (from the 70's) to old Weaver big game scopes and even a Leupold 4-12 on various 22's. Some glass was crystal clear and some made everything darker and a little blurry at really close range. In all instances though, all let me hit my target, and especially on game. Having said that, the first time I had to hit a really tiny target at a fair distance really made me appreciate the fine duplex reticle and shorter distance parallax adjustment of a true .22 scope. In my case, it was a Leupold "Rimfire Special" 4x. I would think the longer tube of the Leupold 2-7 rimfire would look great on your Ruger!