I have shot quite a few Hornady .224 40-grain V-Maxs and Varmaggedon Tips at ground squirrels and prairie dogs in several cartridges from the .22 Hornet to .223 Remington. Both work very well, but the finest accuracy often depends on the specific rifle.

“Montana seems to me to be what a small boy would think Texas is like from hearing Texans.”
John Steinbeck