I’ve got a pulsar thermion2XP 50 that’s currently mounted on another 22-250. I’ve shot several coyotes with it between 250-350 yards. It’s a pretty amazing piece of equipment. I just bought the Ruger because I didn’t want to thread any of my other 22-250’s plus the Ruger has a 1-10” twist barrel so I’ll have the option to run heavier bullets. I bought the pulsar right before they introduced the LR model (laser rangefinder). Currently any yotie I see inside of 300 is pretty much a layup. The optic has good enough resolution that shots to 500 or more could easily be made IF I knew the range.