I have a ruger American predator in 6.5 grendel.
I run Sierra 85g jhp for coyote to 600 yards.
If I had to choose 1 bullet for coyote to deer it would be noslers 100g hbt.
Noslers 100g hbt has dropped every deer, goat out here with 1 shot, never a follow up, course my shot placement has to do with that. Killed em from 51yds to 468 yds so far.
85g at 2923 fps, 100g at 2715fps
Accurate as heck