If you are into the reloading part of shooting, the powder Enforcer is relatively new, I think, and it capable of generating some great velocities without a corresponding increase normally seen in pressure for the 45ACP.

I have recently tried it in some loads I'm working on, 230g cast, and have shot them through a Commander with great results. However I haven't shot them through my chronograph for documentation purposes yet. The recoil was a notable increase yet the cases weren't ejecting into the next county. I think this powder has some great potential for use in 45ACP rounds for this kind of work dealing with bears