I have had couple of those Model 7 Predators in 22-250, and still have one of them. My first one really liked the 52 grain Speer HP. I'm shooting a 40 grain VMax with Varget powder in my current one, and it's like a laser out to 300 yards, a very good shooting rifle. I've had some more 22-250's in the past, and used 4320, H380, W760, and probably a few others that I can't remember. For some reason, I've never tried the 55 grain bullets in one, although I did try some 60 grain SP's trying to maybe work up a load for deer, but the accuracy just wasn't there.
