No, I've read that by the 70's S&W standardized the heat treatment across all the models. The cylinder would likely hold up fine with pressures above 45 +P but the cumulative wear and tolerance stacking will take a toll on the piece overall. Also, there aren't a whole lot of knowledgeable gunsmiths or spare parts left out there these days to bring a gun that's been run hard back to fighting trim.
Somewhere around 20 years back Dave Scovill (yeah, I know that's a dirty word with some) answered a reader's question on the 25 and said that it shouldn't be loaded heavier than the start loads in the Ruger Only section of Speer #13. YMMV.
