I think Riflecrank is correct, feeding issues would be minimal if any. Any issues would probably be more of an individual specimen variation.

This thread was a memory joggers for me. I have an unfired (except factory) early production stainless 375 Ruger take-off barrel, minus the front sight insert and rear sight assembly. And I have a stainless Ruger Mark II in 300 Winchester. If I recall correctly the 300 has had 20 rounds down the barrel since purchasing in the mid 90's. This might be a fairly economical path for me to an additional 375 Ruger.

The 375 & 416 Rugers are probably my favorite cartridges of those calibers.
I agree the 416 Ruger is under appreciation.