I think people worry way too much about mag vs no mag primers. Reduce it 10% if it concerns you and run it over a chrony. If it doesn't shoot well try a different primer. I run cci250s in 90% of my large primer loads. Even my 22-250 benchmark and 40g nbts run cci 250s. Occasionally I find a load that does better with a standard 400 or 200 but most of the time I do great with nato 41s or 250s. If anything in my 28 nos or ultramags I'll go fed 215s or win mag lrs for extra heat. Other than that it's generally cci 41s or 250s. Occasionally a 400 brings things together better in a 6 arc or 223.

In pistols I'll always give a mag primer first option. People really worry if the recipe calls for a standard but I'll always choose a mag pistol primers first. Maybe because I'm not a good enough shot with a pistol to tell the difference so I I'll lean towards effective ignition every time.

Bb