375 Win is a very capable big game cartridge, especially with the Barnes originals. A Yukoner on here, his son took a nice 50+ inch antlered bull moose with the 375 win.
The guy who bought my 375 Win, anchored a brown bear at less than 20 ft. He knocked the front end outta the bear.
My son lobbed a 255 grainer out to 170 yds or so, at a nice fat bull caribou. It was like a lightswitch went off. I honestly haven't seen much difference in field performance over my old marlin in 444 marlin.