My two 357 handgun killed deer were shot with a Lyman 357446 wheel weight metal and 12 grains of old Hercules 2400. Target of opportunity at 25 yards. Between eye and ear. (illegal 2 3/4" barrel). Second was 358156 gas check, linotype, 14.5 Alliant 2400. 6 1/2 Blackhawk. Heart/lung. Fifty yard sprint. No bullet recovered, through shot, no evident expansion but looked like it went straight throug, clipping as rib.
Don't know velocities but the gas check load is what goes in my Ruger and Henry. single shot this season.