I'm not aware of any factory options, much less being in stainless for wet Alaska. Am I missing something or will this need to be a custom build? I've been looking at having a left handed 375 Ruger rebored to 416 Ruger by JES Reboring (done great work for me previously) but I am not sure if he does 416 caliber.

Yes, I know a 375 Ruger will work. It's just, for certain areas that I hunt there's no possibility of longer than 80 yard shots and it's just as likely I'd find a grizzly bear at 5 yards.