I have almost never fired a factory load in my rifles. That being said, I have seen several misfires with Hornady factory ammo. That is totally dependent upon who supplies their primers. I REALLY like Hornady Interlocks and have killed a truckload of deer with them. I am not as much of a fan of the ELDX, but the ELDM are very accurate and work well on deer. I have also been adequately pleased with their brass.
I am sure that there are complaints about any ammo at some point, but Hornady needs to step it up a bit on their ammo.