I have a VXIII 1.5-5 on my 375 in Talley QD rings. Also have a 1.5-6 Kahles with illuminated reticle and a 2.5-10 Bushnell Elite 4500 in Talley rings AND a Talley peep. IHMO with a grand total of 2 safaris to my credit, the 1.5-6 Kahles would have covered all of the bases with maybe one of the other scopes along for a spare. The 1.5 power has been fine for close work like finishing DG and I have shot to a little over 300 yards with it on PG at the higher power. Any reliable scope in that range should serve you well with a spare possibly complementary scope in QD rings as a backup.
