This happened to me yesterday. SD of 5.3 FPS and extreme spread of 12.8 FPS was the largest group with one of my 308 rifles.
That said, I may go back and tweak the seating and see what's what.
What I will state is that almost every last time I was shooting at 600 yards and watched the chrono the load that produced the lowest ES and SD and then went and looked at the holes in the paper I was never happy. The lowest ES and SD just never produced best accuracy.
.
+1
dave