Like the OP, I've also had good results using a relatively light Barnes bullet on a large boar hog. In this case I was using a 127 grain LRX out of a 6.5 Creedmoor. The 250+ pound boar (didn't actually weigh it) ran 20-30 yards and collapsed after I shot it behind the shoulder at about 150 yards.

I'm now thinking my son and I will use 168 grain TTSX loads in .30-06 and .300 Win Mag on a moose hunt we're doing this fall in B.C. I've killed a couple of good sized bull elk with a 168 grain TTSX load in my .30-06, so that gives me some confidence in using that bullet on moose.

[Linked Image from i.imgur.com]