It all depends on what you want the load to do. If all you want is a mild and pleasant load to shoot, stay with Unique loads suggested. If you want a more powerful load or better performance from the gun/cartridge, try the 2400 loads. Modern guns will safely withstand pressures about 50% higher than the standard load at 850 FPS. 15-16 grains of 2400 and a velocity near 1,000-1,100 FPS is fun and manageable and a heck of a powerful load for any task the pistol can be asked to perform.
