3300 is easy with Varget.

I haven't tried the two powders you mentioned, with this bullet in the 30-06 case.

Coached a new hunter a few years back. She had a lightweight 308 that was beating her up at the rifle range. I handloaded some 125 Nosler BT's to about 3100 fps for her. Recoil was greatly reduced. Accuracy was excellent.

We went hunting and she took a fat whitetail buck at about 120 yards. Flattened him with one shot. The bullet went through both shoulder blades and was recovered, quite expanded, under the off-side hide.

I don't know that I'd push that bullet much harder than 3100 fps... After that, there's the 130 gr Barnes TTSX..

Regards, Guy