I've used my 375 Wby a fair bit for lopes/deer and course chucks,yotes, beer and elk. It'll do the job and I see no reason why not to.

As for over kill, I think of over kill as walking up to your fallen animal and then emptying the rest of the rounds in your gun into it.

Dober

"True respect starts with the way you treat others, and it is earned over a lifetime of demonstrating kindness, honor and dignity"....Tony Dungy