I wouldn't overthink this. I used to use 120's and 140's for deer and never had a problem. I had one load with a 139 hornady that I thought was moving at 3400 because it would just mow deer down. I got the chronograph and found that it was only going 3100. One bullet that I would like to try is the 140 grain accubond. It seems like it could do it all from deer to elk.