N165 is absolutely worth trying as a possible better option. I have been around several of these and never witnessed anything other than great results. The velocities are very good at 3200 fps and brass life with max charges is outstanding. I ran 63.5 grains with Nosler 140 projectiles, just drop back a bit, work up, and let her eat....
RL19 worked better than 22 for me when testing, and IMR4831 was my go to till I tested N165. RL22 is good, but there are some burn rates that exceed it. N560 would definately be on my short list as well if I still ownred a 280 AI.
