I don't have a .450, but with the Ballard rifling, I don't see why you couldn't or wouldn't. My 1895 Cowboy in 45-70 does great with the Lyman 457193 (405 gr RNFP).
Someday I hope to be the person my dogs think I am . . . The only true cost of having a dog is its death. Someone once said "a nation of sheep will beget a government of wolves." Shiloh Sharps . . . there is no substitute. NRA Endowment Member