Hoo Boy!
Another reason that I stick with One Caliber, One Powder, and One Primer!
308 Win, Varget, and Fedearl 210M primers.
A guy simply cannot get enough Varget in the case to blow it up.
The Max load is 46 grains (+/- with 165 grainers) and that fills the case to the shoulder.
I am looking at adding a caliber and I suspect that I will choose one based upon the ability to use Varget (makes the 223 and teh 375 H&H good candidates).
Less room for error is a good thing.
BMT