domit,
Li'l Gun provides by far the best velocity-to-pressure ratio of any powder in the .22 Hornet. Here's the data for 45-grain Hornady bullets from Hodgdon:
Powder Velocity Pressure
H110/W296 2574 43,000
Li'l Gun 2787 31,600
H4198 2400 32,000
IMR4227 2484 42,000
Pressure is perhaps the majar factor in case life, and Hornet's are notorious for short case life, partly because the brass is thin and partly because handloaders often hot-rod the little case.
Li'l Gun provides plenty of zip with low pressure. Along with higher velocities and fine accuracy, I've experienced longer case life since switching to Li'l Gun exclusively in the .22 Hornet.
