One of my favorite quotes from Petzal involved his comparison of the .300 mags to the .338 Winmag..

I don't have the book right here at hand, so this is probably not an exact quote, but it went something like this..

" I know that a rifle that shoots a 250 grain bullet at 2600 is going to kick more than one that shoots a 200 grain bullet at 2800, but not THAT much more... It's kind of like getting worked over by a good heavy weight, and then getting worked over by a good light heavy. They both hit REALLY hard, and if I am going to get kicked that hard I want a heavy bullet.

The effect of a heavy medium caliber bullet on game has to be seen to be appreciated. "