For several years my go-to load for .41 Magnum was 16.0 grains of 2400 under an LBT 220 grain WFN, both gas checked and plain base. It got almost exactly 1200 fps from a 6 �� Blackhawk. The plain base did not lead with my alloy and revolver dimensions but at that speed it could produce leading in another revolver. But I liked it because it was relatively mild and superbly accurate.
IIRC that was the starting load listed in the Hornady manual for their 210 grain XTP. 2400 is a very good powder for loads in the 80% range or there abouts since it maintains its ballistic uniformity and accuracy even when loaded down 20 or 25% from max. I have seen that well behaved property across the board in the .357, .41, .44 Special and Magnum and the .45 Colt.
