My old Dupont data lists 17.5 grs. of SR 4759 for 3040 fps. and the same charge with IMR 4227 for 3085 fps. This with the 45 gr. Sierra spitzer and a COL of 2.19 inches. This is pressure tested at 51,000 and 51,400 cup.
Since both of these powders are just capable of reaching the 3000 fps you desire, I wouldn't try to do that with anything faster. E
even tho I have not worked up a data sheet with 4759 like I have with Blue Dot, I am in the middle of load up 200 rounds of 17 grains of 4759 and 50 gr SPSX's, to go after some sage rats in the near future...
these are earmarked for a Rem VSS....
Loads like this are more than adequate for 250 yd varmints.. and are REAL easy on the barrels throat, even when one gets a little overzealous on the trigger in a target rich environment..