The boned meat from a big animal usually runs around 1/3 of live weight. With a 1000-pound moose that means something over 300 pounds.
I've gotten 130 pounds of boned meat into a 120-quarter cooler, but that was unfrozen meat, not cut and wrapped. My guess is that you'll need at least three coolers and maybe four, depending on which way the meat goes in 'em.
