I shoot the 300gr SAF's from my .375 H&H and they shoot very well out to 300 yds (1.5"). Blew up a Cape Buffalo last summer in Zim. I love the bullet and think it will perform very well.
Are there better choices for long range accuracy? Yes. Will it matter out to 400 yds? No.
Now if you have aspirations for 500 plus yards then you may want to consider a higher BC bullet for the possible winds that you may encounter.
Good luck. You'll have fun
