I have shot at least 10 deer with 130gr SST in my .270. Impacts ranged from under 100yds to just over 500yds, and I have no complaints. They exited all the deer I have shot with them, and the deer expired quickly.
I would use them in any rifle for sub 300lb animals. I had some bad experiences with the early 130gr NBT and haven't shot anything but varmints with NBTs since.
I am actually considering trying to get my .270 to shoot SST and GMX to same POI so I can practice and deer hunt with one, and switch to the other for elk, moose, sheep and bear.