http://www.chuckhawks.com/reduced_big_bore_loads.htm shows some reduced recoil loads from Nyati, Inc. using Accurate 5744. Hunting loads use TSX - some 235- and 300-gr at 2000 fps. I guess they expect the TSX to expand OK at these speeds.

Reduced loads given for 9.3x74R and various .375 calibers H&H up.

The 2000-fps loads should shoot about as flat as factory .30-30, and could be used where a .30-30 would work.