You would need a .464 cal. barrel. Twist stab. will most likely not work with the 2,8" projectile length.
Getting the rifling to engage without bumping the shoulder would probably be an issue as well.
At least weight carries up front.
For method of propulsion muzzle loading is the way to fly.
Make sure of a healthy crimp, lest you ram the bullet while seating the cartidge.
An other thing to watch is primer temp sensitivity. The hot gases may set it off. Accuracy will not be to good...,
but, per your request for stabilizing a cartridge, you would have not only the bullet flying, but the rest of the components as well - more metal in the air.
The only advantage over just sticking with stabilizing a .308 projectile.
