I use IMR 4350 for practice and Marmot/P-dog use. 81-82 gr and the Hornady 270 SP gives just over 2700 in my Alaskan.

For 270 TSX bullets I use the max listed of RL-15 and get almost exactly the same speed but the POI changes a little. Both loads are varmint rifle accurate with only a 1.5-5 VX-III. I've shot the Hornady out to 400 yds. on steel with great results.