I wasn't able to get the 2012 or 2011 Rem ballistics pdf to download but i was successful with the 2010.

With the bullet weights cited the 400 yd difference is 2.5"......at 500 yds it's 9.4".

On a prairie dog size target at 400 yds a difference of 2.5" might make a difference.
On a coyote size target at 400 yds a difference of 2.5" is not as significant.

Not unless Remington developed a magical 20 caliber bullet between 2010 to 2012.