Also late to the party here. I put a Bedrug in my '06 Dodge Ram 1500 when the truck was new and would highly recommend it. Not only does it protect the bed (if that's important to you), but it also provides a higher level of protection for what you're hauling. I use the shop-vac to clean it and a garden hose for anything that won't come up with the shop-vac. It looks just like it did the day I put it in.
If you've got Ram boxes or similar sidewall storage you may have issues with the fit. The company will advise of any issues when you send them your configuration.
I've also used it for a hotel room in a pinch. Just throw the air mattress back there and then the sleeping bag. With the Truxedo cover it's comfy and rainproof.
