Johnny Rowland of 460Rowland.com came up with the idea for the cartridge, but the does things with it that Clark will not do as far as the pistols he sells barrels for and what shoots in what, and I personally think I'd take Clark's advice. This is a powerful cartridge, deserves respect and safe practices. I would listen to Clark - and others with experience with the round - and keep .45ACP ammo out of 460 Rowland chambers. Like Gibby said, you can switch back and forth between barrels - or just have two 1911's (my choice!).