I am going to load 150 grain .270 Win Partitions starting at median load and working up to 59 grains. I will stop where accuracy is best provided velocity is acceptable. If I can't get decent results, I know that 58 grains of H-4831 will work.
Other hunters have gotten excellent results using IMR-4350, which I have. I might try a few to see what happens.
A hundred FPS one way or the other ain't gonna matter. That a bullet will go where's it's supposed to go does matter.