Not that the 25-06 isn't a great cartridge, I've just never liked it. It really is at its best with a 24" barrel, and I'd sooner use a 22" bbl.

Really, were I wanting a 25 cal for deer it'd be a Roberts.

Otherwise, 270 all the way...

“Perfection is Achieved Not When There Is Nothing More to Add, But When There Is Nothing Left to Take Away” Antoine de Saint-Exupery