I am a "KISS" fan myself. No need to over complicate things.
I do have several rifles that will put loads for, say, prairie dogs to the identical POI as, say, deer loads and I've brought those out west when prairie dogs & coyotes were on the docket in one place and big game in another.
On the other hand, if hunting big game in an area with many targets of opportunity like varmints I'll shoot all critters w/ big game loads rather than risk becoming confused in the field and/or end up fartin around when I should be shooting.
