I have a 22-250 Savage 1:9 twist, using 65 gr sierra sbt, 29.7 gr Hodgdon H4895, ogive 2.090. This combo shoots great out of my gun, I shot 12 rounds of virgin brass at 100yds and shot 1 hole, just wanted to shoot the brass, was pleasantly surprised. Tried hotter loads but this combo works for my gun. Started with powder charges, then when I found the right load, tried different lengths starting 10 thousandths back, until I found the sweet spot. Don't own a chronograph, but would like to know the muzzle velocity. Snuzem, try different loads, but the 65's shoot great out of my Savage