Not a handgunner, hence the stupid question...if you had Python, the best Smith, or a Dan Wesson and a Ransome Rest under identical conditions...which would be likely to take the honors?
Accuracy only, no ergonomics, no cosmetics, no personal bias.
I would take one not mentioned: the Colt Officers Model Target (pre war) or the Officer's Model Match (post war).
The pre war guns were specifically wadcutter guns and the forcing cones were abrupt specifically for their use. The later models are a bit more forgiving with many bullet shapes.
These guns were dimensionally .358-.357 throat, .356-.357 groove as well.
Pythons and Smiths post war were often tight for throat diameter and Pythons were also 9mm ish for groove.
A friend of mine was a half scale champion and he preferred the Python he had to all others, but it was also dimensionally sound. .358 throats, .356 groove.
DWs were/are often in need of a gas check. They shoot great but are a bit rough for lead.
I have a Smith 41, 17, 18 and 48s here, along with several 14s,15s,38-44s, 36s, 67s and 10s.
Even several other Colt guns. The OMTs and OMM 22/38's and probably the 32 Colt NP in the same if I had one are consistently the most accurate production revolvers Ive come across.
