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Originally Posted by The_Real_Hawkeye
Originally Posted by dogcatcher223
I read an article today out of a local paper. They said 66% of all covid cases here are "breakthrough" cases in vaccinated people. Then they blamed unvaccinated people for getting the vaccinated people sick!

Doesn't even begin to make logical sense. Being vaccinated is supposed to protect you from those who might pass it to you. If it doesn't, it's worthless. Furthermore, its the vaccinated who are the variant factories. A virus doesn't need to make variants in the bodies of unvaccinated people because, in theory, they have no defense against the seminal version.
That right there is bullshyt. Viruses can and do mutate in anyone infected. Viruses do not have intelligence so it's not like they say to themselves "oh shyt, these folks are vaccinated so I need to mutate to overcome it" . The latest variant of concern, the Mu variant came out of South Africa where very few are vaccinated and Delta originated in India which also has a very low vaccination rate comparatively.

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The more it reproduces the more it will mutate.


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Originally Posted by Blackheart
That right there is bullshyt. Viruses can and do mutate in anyone infected. Viruses do not have intelligence so it's not like they say to themselves "oh shyt, these folks are vaccinated so I need to mutate to overcome it" . The latest variant of concern, the Mu variant came out of South Africa where very few are vaccinated,

You're ignorant. It's about environmental pressure to adapt. The unvaccinated don't provide adaptive pressure to the virus, since they have (in theory) no immunity to the seminal form. Only the vaccinated, in theory, have immunity to the seminal form, so pressures to favor mutations would only be present in them.

You clearly lack basic biological understanding.

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Originally Posted by The_Real_Hawkeye
Originally Posted by Blackheart
That right there is bullshyt. Viruses can and do mutate in anyone infected. Viruses do not have intelligence so it's not like they say to themselves "oh shyt, these folks are vaccinated so I need to mutate to overcome it" . The latest variant of concern, the Mu variant came out of South Africa where very few are vaccinated,

You're ignorant. It's about environmental pressure to adapt. The unvaccinated don't provide adaptive pressure to the virus, since they have (in theory) no immunity to the seminal form. Only the vaccinated, in theory, have immunity to the seminal form, so pressures to favor mutations would only be present in them.

You clearly lack basic biological understanding.
I understand that a virus mutation is just that, a mutant. An imperfect replica like a cancer cell in a mammal and that viruses produce a number of them at random. That can happen in one infected person as well as another. Some by chance are viable and some are not. Occasionally one superior to the parent is produced and will become dominant as is the case with Delta. If it were different, then how do you explain the fact that the most variants are not coming out of the most highly vaccinated Countries ? If vaccines encourage more variants then Israel, with the highest vaccination rate as well as the highest infection rate, should be throwing out variants like deflave throws out insults.

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Just who is providing the verifiable laboratory results proving the existence of variants, and what is their methodology?
Have they singled out and clearly identified the original variant? How do they know it is original and how was it found?

Hmmmmmmmm.....

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Originally Posted by Blackheart
Originally Posted by The_Real_Hawkeye
Originally Posted by Blackheart
That right there is bullshyt. Viruses can and do mutate in anyone infected. Viruses do not have intelligence so it's not like they say to themselves "oh shyt, these folks are vaccinated so I need to mutate to overcome it" . The latest variant of concern, the Mu variant came out of South Africa where very few are vaccinated,

You're ignorant. It's about environmental pressure to adapt. The unvaccinated don't provide adaptive pressure to the virus, since they have (in theory) no immunity to the seminal form. Only the vaccinated, in theory, have immunity to the seminal form, so pressures to favor mutations would only be present in them.

You clearly lack basic biological understanding.
I understand that a virus mutation is just that, a mutant. An imperfect replicant like a cancer cell in a mammal and that viruses produce a number of them at random. That can happen in one infected person as well as another. If it were different, then how do you explain the fact that the most variants are not coming out of the most highly vaccinated Countries ? If vaccines encourage more variants then Israel, with the highest vaccination rate as well as the highest infection rate, should be throwing out variants like deflave throws out insults.


You miss the point. Virus’ mutate equally in vaccinated and unvaccinated people. As a general rule, mutations are a net negative to the organism; a genetic change that makes them less fit to survive. In an unvaccinated host, the mutation has no benefit and the negative consequences of the mutation cause it to go extinct Only in a vaccinated environment will the negative consequence of the mutation be outweighed by the survival advantage and out-reproduce the standard issue version.


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Regardless of what happens in the next few months, the most deadly variation will be peaking about 1 month before the mid term election.


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Originally Posted by kingston
Originally Posted by Kenneth
"If you peer deeper, you’ll generally find this: The vaccinated remain substantially protected against serious illness or death, but the unvaccinated are entering the hospital and dying at very high rates indeed, "

Out of the numerous paragraphs in your post,

Any discussion here on the above quote, that paragraph is fact or not?


You've got to read it in context. The rest of the paragraph.

"If you peer deeper, you’ll generally find this: The vaccinated remain substantially protected against serious illness or death, but the unvaccinated are entering the hospital and dying at very high rates indeed, as if to compensate. Thus Israel has maintained the same case fatality rate of around 0.7%, before and after mass vaccination. If this is just Delta being more dangerous, then we would expect countries with lower vaccination rates to be enduring truly staggering mortality right now, but they are not. In heavily vaccinated countries, Delta is raging with a rare fury among the unvaccinated, but in lesser-vaccinated countries it is doing nothing unusual. This means that the efficacy statistics are broadly unreliable. The exact reasons don’t really matter: Either the vaccines have the power to change the whole picture, or they don’t."


Kingston, you are assuming same levels of exposure between heavily vaccinated populations (Israel) and (countries with lower vaccination rates)

another way to read it - don't be an un-vaccinated person in a highly vaccinated country, if you can help it.


Originally Posted by jorgeI
...Actually Sycamore, you are sort of right....
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Originally Posted by JakeBlues
Regardless of what happens in the next few months, the most deadly variation will be peaking about 1 month before the mid term election.


wait, we were told this was all going away right after the last election? it was all made up and stuff. remember?


Originally Posted by jorgeI
...Actually Sycamore, you are sort of right....
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Originally Posted by Dutch
Originally Posted by Blackheart
Originally Posted by The_Real_Hawkeye
Originally Posted by Blackheart
That right there is bullshyt. Viruses can and do mutate in anyone infected. Viruses do not have intelligence so it's not like they say to themselves "oh shyt, these folks are vaccinated so I need to mutate to overcome it" . The latest variant of concern, the Mu variant came out of South Africa where very few are vaccinated,

You're ignorant. It's about environmental pressure to adapt. The unvaccinated don't provide adaptive pressure to the virus, since they have (in theory) no immunity to the seminal form. Only the vaccinated, in theory, have immunity to the seminal form, so pressures to favor mutations would only be present in them.

You clearly lack basic biological understanding.
I understand that a virus mutation is just that, a mutant. An imperfect replicant like a cancer cell in a mammal and that viruses produce a number of them at random. That can happen in one infected person as well as another. If it were different, then how do you explain the fact that the most variants are not coming out of the most highly vaccinated Countries ? If vaccines encourage more variants then Israel, with the highest vaccination rate as well as the highest infection rate, should be throwing out variants like deflave throws out insults.


You miss the point. Virus’ mutate equally in vaccinated and unvaccinated people. As a general rule, mutations are a net negative to the organism; a genetic change that makes them less fit to survive. In an unvaccinated host, the mutation has no benefit and the negative consequences of the mutation cause it to go extinct Only in a vaccinated environment will the negative consequence of the mutation be outweighed by the survival advantage and out-reproduce the standard issue version.
Then why did Mu come out of South Africa where almost nobody is vaccinated ? As I understand it, mutations are completely at random. Most will be inferior in one way or another to the parent and will quickly die out but occasionally one that is superior in transmission and/or rate of replication to the parent will happen and it will then become dominant. If this is not how it works then we should see no more mutations beyond Delta as it is clearly able to infect, replicate and be transmitted quite effectively among the vaccinated. No ?

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Almost nobody is not nobody.....

Second, it was first found in SA, we really don’t know where it came from.


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Originally Posted by Dutch
You miss the point. Virus’ mutate equally in vaccinated and unvaccinated people. As a general rule, mutations are a net negative to the organism; a genetic change that makes them less fit to survive. In an unvaccinated host, the mutation has no benefit and the negative consequences of the mutation cause it to go extinct Only in a vaccinated environment will the negative consequence of the mutation be outweighed by the survival advantage and out-reproduce the standard issue version.
Let me see if I can get the disease causing virus mutation process straight. In an unvaccinated population a virus does better if it can become more contagious and less deadly? A function of not killing the host and being able to be carried around to new hosts? In a vaccinated population maybe the more benign mutations are controlled by the ''vaccine'' and the normal process of mutation is altered to maybe allow deadlier versions to evade the vaccine and escape into the population?


Patriotism (and religion) is the last refuge of a scoundrel.

Jesus: "Take heed that no man deceive you."
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Originally Posted by Dutch

You miss the point. Virus’ mutate equally in vaccinated and unvaccinated people. As a general rule, mutations are a net negative to the organism; a genetic change that makes them less fit to survive. In an unvaccinated host, the mutation has no benefit and the negative consequences of the mutation cause it to go extinct Only in a vaccinated environment will the negative consequence of the mutation be outweighed by the survival advantage and out-reproduce the standard issue version.

Prezactly.

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Originally Posted by The_Real_Hawkeye
Originally Posted by Dutch

You miss the point. Virus’ mutate equally in vaccinated and unvaccinated people. As a general rule, mutations are a net negative to the organism; a genetic change that makes them less fit to survive. In an unvaccinated host, the mutation has no benefit and the negative consequences of the mutation cause it to go extinct Only in a vaccinated environment will the negative consequence of the mutation be outweighed by the survival advantage and out-reproduce the standard issue version.

Prezactly.
Then we will see no more mutations beyond Delta since it is clearly able to infect, replicate and transmit through the vaccinated quite effectively no ?

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Originally Posted by Blackheart
Then we will see no more mutations beyond Delta since it is clearly able to infect, replicate and transmit through the vaccinated quite effectively no ?

Each vaccinated person can favor a wide variety of mutations. No reason to assume they'd only favor one particular mutation from the seminal form.

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Originally Posted by Sycamore
Originally Posted by kingston
Originally Posted by Kenneth
"If you peer deeper, you’ll generally find this: The vaccinated remain substantially protected against serious illness or death, but the unvaccinated are entering the hospital and dying at very high rates indeed, "

Out of the numerous paragraphs in your post,

Any discussion here on the above quote, that paragraph is fact or not?


You've got to read it in context. The rest of the paragraph.

"If you peer deeper, you’ll generally find this: The vaccinated remain substantially protected against serious illness or death, but the unvaccinated are entering the hospital and dying at very high rates indeed, as if to compensate. Thus Israel has maintained the same case fatality rate of around 0.7%, before and after mass vaccination. If this is just Delta being more dangerous, then we would expect countries with lower vaccination rates to be enduring truly staggering mortality right now, but they are not. In heavily vaccinated countries, Delta is raging with a rare fury among the unvaccinated, but in lesser-vaccinated countries it is doing nothing unusual. This means that the efficacy statistics are broadly unreliable. The exact reasons don’t really matter: Either the vaccines have the power to change the whole picture, or they don’t."


Kingston, you are assuming same levels of exposure between heavily vaccinated populations (Israel) and (countries with lower vaccination rates)

another way to read it - don't be an un-vaccinated person in a highly vaccinated country, if you can help it.


The quoted text is saying the data is flawed. Yet you try to make a case based on the data?


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If you put Taco Bell sauce in your ramen noodles it tastes just like poverty
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Originally Posted by UncleAlps
The more it reproduces the more it will mutate.


Spot on!


Originally Posted by 16penny
If you put Taco Bell sauce in your ramen noodles it tastes just like poverty
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Originally Posted by The_Real_Hawkeye
Originally Posted by Blackheart
Then we will see no more mutations beyond Delta since it is clearly able to infect, replicate and transmit through the vaccinated quite effectively no ?

Each vaccinated person can favor a wide variety of mutations. No reason to assume they'd only favor one particular mutation from the seminal form.
It seems that if Delta is able to infect, replicate and transmit through the vaccinated just fine, then it would be no more or less likely to produce a mutant strain than in an unvaccinated host. In other words if the vaccine is no hurdle to Delta then how is a vaccinated host any more likely to produce a successful mutation than an unvaccinated host ?

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Originally Posted by dogcatcher223
I read an article today out of a local paper. They said 66% of all covid cases here are "breakthrough" cases in vaccinated people. Then they blamed unvaccinated people for getting the vaccinated people sick!

Morons.

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Originally Posted by Blackheart
Originally Posted by The_Real_Hawkeye
Originally Posted by Blackheart
Then we will see no more mutations beyond Delta since it is clearly able to infect, replicate and transmit through the vaccinated quite effectively no ?

Each vaccinated person can favor a wide variety of mutations. No reason to assume they'd only favor one particular mutation from the seminal form.
It seems that if Delta is able to infect, replicate and transmit through the vaccinated just fine, then it would be no more or less likely to produce a mutant strain than in an unvaccinated host.

What is your point?

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