That wrist pain that can affect accuracy is something pretty common with people who have shot thousands and thousands of rounds per year, year after year.
Not many people get to that point. It's good to know that I'm not the only one.
I believe I saw something on TV years ago that a skeleton of a man who shot handguns a lot was ID'd from the evident punishment in his shooting hand wrist.
Pretty sure it doesn't have to be "magnum" ammo type shooting either, but that would certainly speed things up.